Attempts to measure sensitiser photophysics in opaque tissue.

The photochemistry of sensitisers for photodynamic therapy

The preparation and photophysical properties of a number of water-soluble metallated phthalocyanines are described. These compounds have been shown to be effective photosensitizers for the destruction of tumours. The photophysics of various aluminium phthalocyanines of different degrees of sulphonation, from mono (S1) to tetra (S4); and of various disulphonated (S2) regioisomers was shown to be...

Nasopharynx- The Secret Vault for Lost Foreign Bodies of the Upper Aerodigestive Tract

Introduction: Foreign bodies in the upper aerodigestive tract often get lost following inappropriate attempts at removal. Children may present late with localized infection, posing a challenge to the otolaryngologists in a referral set-up in diagnosing and retrieving such foreign bodies.   Case Report: A two-year-old boy presented with refractory purulent rhinorrhea and intermittent low-grade f...

Attempts to Vaccinate Foals with Living Tissue Culture Adapted Horse Sickness Virus

Nasal colonization with Streptococcus pneumoniae includes subpopulations of surface and invasive pneumococci.

We demonstrated that during colonization with Streptococcus pneumoniae the nasal mucosal tissues of mice support two populations of pneumococci. Transparent-phase pneumococci can be readily washed from the outer surface, while a second population composed of primarily opaque-phase pneumococci is released only by homogenization of the nasal tissue. The fact that the opaque phase has previously b...

Salbutamol-Induced Desensitization and Attempts to Resensitize In Vitro

The study was carried out to desensitize spontaneously active isolated chick rectum with salbutamol in log doses starting from 100 nanogram and resensitize with various drugs as a result to revive the desensitized tissue and respond to Salbutamol. The tissue response after desensitization to alpha, beta adrenergic and muscarinic acetylcholine receptor antagonists was isotonically recorded for 1...